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The sperm nucleus: chromatin, RNA and the nuclear matrix




A Sperm Cell or Spermatozoa
This study was undertaken to determine whether the increased pregnancy outcome was attributable to the preferred nuclear morphology of the selected spermatozoa, and not to the special sperm preparation technique modified by IMSI. RESULTS: Implantation and pregnancy rates were significantly higher, and abortion rates significantly lower, in the positive group compared with the negative group Sperm with a morphologically abnormal nucleus usually have low fertility potential, but some with certain nuclear abnormalities may still be able to produce pregnancy following ICSI. Sperm morphology has been recognized as the best predictor of outcome for natural fertilization Bartoov et al. Recently, increasing evidence has suggested that sperm morphology also plays a significant role in ICSI outcome Bartoov et al.



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The mature sperm cell spermatozoa is 0. It consists of a head, body and tail. The head is covered by the ac cap and contains a nucleus of dense genetic material from the 23 chromosomes. It is attached from the neck to the body containing mitochondria that supply the energy for the sperm's activity. The tail is made of protein fibers that contract on alternative sides, giving a characteristic wavelike movement that drives the sperm through the seminal fluid, which also supplies additional energy.

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